Advancing our understanding of the neurobiology of anorexia nervosa: translation into treatment
About this resource
Anorexia nervosa (AN) is a severe mental disorder predominantly affecting young women. Less than half of patients recover following treatment. For the past 20 years, substantial research has been invested into the identification of the neurobiological underpinnings. Structural brain imaging studies have shown gray and white matter changes which generally normalize with recovery. Functional brain imaging studies have demonstrated alterations in fronto-striato-limbic circuits, suggesting aberrant cognitive control, reward, and emotion processes. This suggests AN psychopathology emerge as a result of altered interactions between top-down and bottom-up circuits, possibly related to core disturbances in how the brain processes salient stimuli. Below we point to examples of how advances in our understanding of the neurobiology of anorexia nervosa, focusing on neuroimaging studies of brain structure and function, can be translated into treatment.
Deep brain stimulation for anorexia nervosa: A step forward
No abstract availableRead more
Multidisciplinary care considerations for gender nonconforming adolescents with eating disorders: A case series
Gender nonconforming youth are at risk for body dissatisfaction and disordered eating.Read more
Gender Dysphoria, Eating Disorders and Body Image: An Overview.
BACKGROUND: Gender dysphoria is a clinical condition in which a state of inner suffering, stress and anxiety is detected when biological sex and a person's gender identity do not coincide.Read more
Association of Bulimia Nervosa With Long-term Risk of Cardiovascular Disease and Mortality Among Women.
Importance: Bulimia nervosa is associated with short-term cardiovascular complications in women, but its long-term consequences on cardiovascular health are unknown.Read more