Structural magnetic resonance imaging in eating disorders: A systematic review of voxel-based morphometry studies
About this resource
This systematic review summarises and critically appraises the literature on structural magnetic resonance imaging in people with a current or past eating disorder. Studies using voxel-based morphometry image analysis were included. Ten studies reported on a total of 236 people with a current or past eating disorder and 257 healthy controls. Sample heterogeneity prohibited a meta-analytic approach. The findings do not unequivocally indicate grey or white matter volume abnormalities in people with an eating disorder. Nevertheless, these preliminary data suggest that, compared with healthy controls, people with anorexia nervosa have decreased grey matter in a range of brain regions and that those with bulimia nervosa have increased grey matter volumes in frontal and ventral striatal areas. Research in the recovery phase and longitudinal studies suggest that potential brain tissue abnormalities may recover with clinical improvement. Overall, as the available data are inconclusive, further efforts in this field are warranted.
Anorexia nervosa: current status and future directions.
Anorexia nervosa (AN) is a serious mental illness categorized by a failure to maintain a minimally normal weight, a fear of gaining weight or becoming fat, and preoccupations about body shape or weight.Read more
NEDC Fact Sheet - Anorexia NervosaRead more
Obsessive compulsive disorder as a cause of atypical eating disorder: a case report.
OBJECTIVE: To describe a case of an atypical eating disorder with a diagnosis of obsessive-compulsive disorder and discuss the phenomenological and neurobiological aspects links between the disorders.Read more
Energy metabolism and body composition in long-term recovery from anorexia nervosa
Objective: The aim of this study was to determine if energy metabolism and body composition differ between women recovered from anorexia nervosa for 2 or more years (RAN) and control (C) women.Read more