Understanding how Vyvanse works to treat Binge-Eating Disorder

About this study

Do you binge-eat at least 3 days a week? Are you distressed about your binge eating? You may be eligible to participate in a clinical trial looking at how the medication VYVANSE works to reduce binge-eating symptoms.

Research TeamA/Prof Michael Kohn, Dr Kristi Griffiths, Prof Stephen Touyz, Prof Phillipa Hay, Prof Simon Clarke, Dr Jonathan Marks, Dr Mayuresh Korgaonkar, Dr Linette Gomes, Dr Gail Anderson
InstitutionThe University of Sydney; Westmead Hospital
Ethics Approval NumberHREC/17/WMEAD/490
Funding SourceShire International GmbH
Project Start Date4 May 2018
Project End Date4 May 2020
ParticipantsYou may be eligible if:
* You are 18 - 40 years old
* You have Moderate to Severe Binge-Eating Disorder
* Your Body Mass Index is 20 - 45kg/m2 - use BMI calculator at
www.health.nsw.gov.au/heal/Pages/bmi.aspx
Whats InvolvedThe trial runs for 8 weeks and you would need to:
* Attend Westmead Institute for Medical Research & Westmead Hospital twice (before medication and after 8 weeks of medication) to complete interviews, questionnaires, cognitive tests, and brain scans.
* Have a blood pressure check at week 2, at Westmead or by your GP.
* Have a doctors appointment at Westmead Hospital at week 4, to check your medication dose.

During the trial, you would not be able to use any other treatments for your binge-eating symptoms.
LocationWestmead
Contact Details

Jenny Yang/0286273321/jenny.yang@sydney.edu.au

See also

Effectiveness of a Stress-Reduction Intervention for Disordered Eating Behaviours

Eating is a common and normal way to soothe, cope with, or distract from stress.

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The role of emotion regulation and interpersonal problems in the relationship between insecure attachment and disordered eating

The way in which people manage their own emotions and interact with others can impact the way they experience their relationships as well as their eating behaviours.

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Acceptance and commitment therapy for eating disorders: Clinical applications of a group treatment

Eating disorders, particularly among adult patients with a long course of illness, are exceptionally difficult to treat.

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Mortality in eating disorders - results of a large prospective clinical longitudinal study.

OBJECTIVE To report on long-term mortality in anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and eating disorder not otherwise specified (ED-NOS), causes of death, and predictors of early death.

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